What should not be included in a resume?

Any information which has relevance to your professional career should be included in the Resume and things which are not directly related to your career can be left out. Further care has to be taken to put in relevant information and not present the minutest of detail.
 
If you have a good number of years in your career then try to comprehensively cover the last 10 years and the rest can be mentioned in brief. For example if a professional has a work experience of 22 years then his Key Responsibility Area in the initial 10 years would have lost relevance and hence a summary of experience can be shared.